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SIRPA antibody

SIRPA Reactivity: Pig WB, FACS, IHC, IP, IHC (p), IHC (fro) Host: Mouse Monoclonal BL1H7 unconjugated
Catalog No. ABIN1819095
  • Target See all SIRPA Antibodies
    SIRPA (Signal-Regulatory Protein alpha (SIRPA))
    Reactivity
    • 72
    • 39
    • 32
    • 9
    • 7
    • 3
    • 3
    • 3
    Pig
    Host
    • 58
    • 32
    • 1
    • 1
    Mouse
    Clonality
    • 57
    • 35
    Monoclonal
    Conjugate
    • 45
    • 11
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SIRPA antibody is un-conjugated
    Application
    • 56
    • 45
    • 19
    • 18
    • 12
    • 12
    • 10
    • 10
    • 8
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    Porcine CD172a, a member of the signal regulatory protein (SIRP) family. Clone BL1H7 was originally clustered as SWC3 at the Third International Swine Cluster of Differentiation Workshop (,). CD172a is expressed on monocyte derived dendritic cells (MoDCs) also conventional (cDCs), plasmacytoid (pDCs) DCs and blood DCs.(, ). Clone BL1H7 immunoprecipitated a single band of ~90-110kD from preparations of biotinylated alveolar macrophages, a result confirmed by Western blotting analysis of alveolar macrophage lysates under non reducing conditions. Has proved a useful and reliable tool for immunohistochemical analysis of routinely processed, formalin fixed, paraffin embedded porcine tissues. Aberrant expression of CD172a has been noted on porcine leukemias with blast cells co-expressing lymphocytic markers CD5 and CD25 whilst expressing the Myeloid marker CD172a in a as opposed to the more characteristic of CD172+ cells seen in normal blood PBMC.
    Purification
    Protein G purified
    Immunogen
    Porcine alveolar macrophages.

    Type of Immunogen: Cells
    Clone
    BL1H7
    Isotype
    IgG1
    Top Product
    Discover our top product SIRPA Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Comment

    Target Species of Antibody: Pig

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    PBS, 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing. Store undiluted.
    Storage
    4 °C,-20 °C
    Storage Comment
    4°C or -20°C, Avoid freeze-thaw cycles. Store undiluted.
  • Target
    SIRPA (Signal-Regulatory Protein alpha (SIRPA))
    Alternative Name
    CD172A / SIRPA (SIRPA Products)
    Synonyms
    BIT antibody, CD172A antibody, MFR antibody, MYD-1 antibody, P84 antibody, PTPNS1 antibody, SHPS1 antibody, SIRP antibody, SIRPA antibody, SIRP-A1 antibody, SIRP-B1 antibody, AI835480 antibody, Bit antibody, CD172a antibody, Ptpns1 antibody, SHP-1 antibody, SHPS-1 antibody, swc3 antibody, signal regulatory protein alpha antibody, myeloperoxidase antibody, signal-regulatory protein alpha antibody, tyrosine-protein phosphatase non-receptor type substrate 1 antibody, SIRPA antibody, MPO antibody, LOC458039 antibody, LOC100400378 antibody, LOC100590224 antibody, Sirpa antibody
    Background
    Name/Gene ID: SIRPA

    Synonyms: SIRPA, CD172A, CD172a antigen, Inhibitory receptors shps-1, Inhibitory receptor SHPS-1, Macrophage fusion receptor, MyD-1 antigen, p84, SHPS-1, SHPS1, SIRP, Sirp-alpha-1, Sirp-alpha-3, Sirp-alpha1, MYD1, SIRPalpha, SIRPalpha2, BIT, MFR, MYD-1, PTPNS1, SHP substrate 1, Sirp-alpha-2
    Gene ID
    140885
    UniProt
    P78324
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