CD4 antibody (FITC)

Catalog No. ABIN1819612

This Rat Monoclonal antibody specifically detects CD4 in FACS, IHC and IHC (fro). It exhibits reactivity toward Dog.

Quick Overview for CD4 antibody (FITC) (ABIN1819612)

Target: CD4

Reactivity: Dog

Host: Rat

Clonality: Monoclonal

Conjugate: This CD4 antibody is conjugated to FITC

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: YKIX302-9

Product Details anti-CD4 Antibody (FITC)

Specificity: Is a monoclonal antibody specific for the canine CD4 cell surface antigen. Clone YKIX302.9 was clustered at the first Canine Leukocyte Antigen Workshop (CLAW) [] along with clone CA13.1E4. Has been demonstrated to partially deplete circulating T lymphocytes when administered in vivo, but alone was not sufficient to prolong allograft survival in a canine transplant model. Uniquely amongst mammals, canine CD4 is expressed by neutrophils as well as by lymphocytes subsets. Forms part of a panel of anti canine monoclonal antibodies used extensively in the evaluation of leukemic status in dogs.

Purification: Protein G purified

Immunogen: Canine Concanavalin A activated T-cell blasts.

Type of Immunogen: Cells

Isotype: IgG2a

Application Details

Application Notes: Approved: Flo (1:1), IHC, IHC-Fr

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Dog

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide, 1 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing. Protect from light.

Storage: 4 °C,-20 °C

Storage Comment: Short term: store at 4°C. Long term: -20°C. Avoid freeze-thaw cycles. Protect from light.

Target Details for CD4

Target: CD4

Alternative Name: CD4

Background: Name/Gene ID: CD4

Synonyms: CD4, CD4 antigen, CD4 receptor, CD4mut, CD4 antigen (p55), CD4 Molecule

Gene ID: 920

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events