Connexin 43/GJA1 antibody (AA 366-382)

Catalog No. ABIN1821131

The Rabbit Polyclonal anti-Connexin 43/GJA1 antibody has been validated for WB and IHC. It is suitable to detect Connexin 43/GJA1 in samples from Human, Rat and Mouse.

Quick Overview for Connexin 43/GJA1 antibody (AA 366-382) (ABIN1821131)

Target: Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Connexin 43/GJA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Connexin 43/GJA1 Antibody

Binding Specificity: AA 366-382

Specificity: Connexin-43. Species crossreactivity: human, mouse, rat.

Purification: Affinity purified

Immunogen: A synthetic peptide corresponding to the amino acids 366-382 from the C-terminus of human Connexin-43.

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Sterile distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS,  pH 7.4, 5 % BSA, 0.05 % thimerosal, 0.05 % sodium azide

Preservative: Sodium azide, Thimerosal (Merthiolate)

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Target Details for Connexin 43/GJA1

Target: Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

Alternative Name: GJA1 / CX43 / Connexin 43

Background: Name/Gene ID: GJA1
Subfamily: Connexin
Family: Ion Channel

Synonyms: GJA1, Connexin-43, DFNB38, Connexin 43, Gap junction alpha-1 protein, GJAL, HSS, Gap junction protein alpha 1, ODDD, ODD, AVSD3, CX43, HLHS1, ODOD, SDTY3

Gene ID: 2697

UniProt: P17302

Pathways: MAPK Signaling, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization