APP antibody (C-Term)

Catalog No. ABIN1821361

This Mouse Monoclonal antibody specifically detects APP in ELISA. It exhibits reactivity toward Human, Mouse and Primate.

Quick Overview for APP antibody (C-Term) (ABIN1821361)

Target: APP (Amyloid beta (A4) Precursor Protein (APP))

Reactivity: Human, Mouse, Primate

Host: Mouse

Clonality: Monoclonal

Conjugate: This APP antibody is un-conjugated

Application: ELISA

Clone: GF1

Product Details anti-APP Antibody

Binding Specificity: C-Term

Specificity: The C-terminal of beta amyloid peptide 42 and full length beta amyloid peptide 42. Species Crossreactivity: mouse, rat, other primates. Does not cross react with beta amyloid peptide 40.

Purification: Affinity purified

Immunogen: Synthetic peptide MVGGVVIA corresponding to the C-terminal of beta amyloid peptide 42 (KLH).

Type of Immunogen: Synthetic peptide

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: distilled water to 1 mg/mL.

Concentration: Lot specific

Buffer: Lyophilized from 0.01 M PBS,  pH 7.2

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Lyophilized powder may be stored at -20°C. Stable for 1 year at -20°C. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Reconstituted product is stable for 1 year at -20°C.

Target Details for APP

Target: APP (Amyloid beta (A4) Precursor Protein (APP))

Alternative Name: APP / beta Amyloid

Background: Name/Gene ID: APP
Family: Amyloid precursor protein

Synonyms: APP, ABPP, A4, ABETA, AD1, Alzheimer disease, Amyloid beta, Beta-amyloid peptide, APPI, Beta amyloid, CVAP, AAA, PN2, PreA4, Amyloid beta A4 protein, Peptidase nexin-II, CTFgamma, PN-II, Protease nexin-II

Gene ID: 351

UniProt: P05067

Pathways: Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour