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Tuberin antibody (Ser1387)

The Rabbit Polyclonal anti-Tuberin antibody has been validated for WB and IP. It is suitable to detect Tuberin in samples from Human, Mouse, Rat and Monkey.
Catalog No. ABIN1823000

Quick Overview for Tuberin antibody (Ser1387) (ABIN1823000)

Target

See all Tuberin (TSC2) Antibodies
Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

Reactivity

  • 273
  • 179
  • 117
  • 8
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Mouse, Rat, Monkey

Host

  • 363
  • 13
Rabbit

Clonality

  • 350
  • 26
Polyclonal

Conjugate

  • 144
  • 32
  • 30
  • 29
  • 21
  • 21
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 6
  • 6
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
This Tuberin antibody is un-conjugated

Application

  • 201
  • 169
  • 122
  • 81
  • 80
  • 62
  • 38
  • 33
  • 20
  • 14
  • 9
  • 7
  • 6
  • 5
  • 2
Western Blotting (WB), Immunoprecipitation (IP)
  • Binding Specificity

    • 35
    • 23
    • 19
    • 19
    • 17
    • 16
    • 15
    • 15
    • 15
    • 11
    • 10
    • 8
    • 8
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    • 7
    • 7
    • 7
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    • 6
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    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Ser1387

    Specificity

    Endogenous levels of human tuberinonly when phosphorylated at (Ser1387). Species Crossreactivity: mouse, monkey and rat.

    Purification

    Affinity purified

    Immunogen

    Synthetic phosphopeptide corresponding to residues surrounding Ser1387 of human tuberin.

    Type of Immunogen: Synthetic phospho-peptide

    Isotype

    IgG
  • Application Notes

    Approved: IP (1:50), WB

    Usage: Western Blot: 1:1000 Incubate membrane with diluted antibody in 5 % BSA, 1X TBS, 0.1 %. Tween-20 at 4 °C with gentle shaking, overnight.

    Comment

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    10 mM sodium HEPES,  pH 7.5, 150 mM sodium chloride, 100 μg/mL BSA, 50 % glycerol

    Handling Advice

    Aliquot to avoid repeated freezing and thawing.

    Storage

    4 °C,-20 °C

    Storage Comment

    May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.
  • Target

    Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

    Alternative Name

    Tuberin / TSC2

    Background

    Name/Gene ID: TSC2

    Synonyms: TSC2, LAM, Tuberous sclerosis 2 protein, TSC4, Tuberin, Tuberous sclerosis 2

    Gene ID

    7249

    UniProt

    P49815

    Pathways

    RTK Signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus
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