Tuberin antibody (Ser1387)

Catalog No. ABIN1823000

The Rabbit Polyclonal anti-Tuberin antibody has been validated for WB and IP. It is suitable to detect Tuberin in samples from Human, Mouse, Rat and Monkey.

Quick Overview for Tuberin antibody (Ser1387) (ABIN1823000)

Target: Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tuberin antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-Tuberin Antibody

Binding Specificity: Ser1387

Specificity: Endogenous levels of human tuberinonly when phosphorylated at (Ser1387). Species Crossreactivity: mouse, monkey and rat.

Purification: Affinity purified

Immunogen: Synthetic phosphopeptide corresponding to residues surrounding Ser1387 of human tuberin.

Type of Immunogen: Synthetic phospho-peptide

Isotype: IgG

Application Details

Application Notes: Approved: IP (1:50), WB

Usage: Western Blot: 1:1000 Incubate membrane with diluted antibody in 5 % BSA, 1X TBS, 0.1 %. Tween-20 at 4 °C with gentle shaking, overnight.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM sodium HEPES,  pH 7.5, 150 mM sodium chloride, 100 μg/mL BSA, 50 % glycerol

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.

Target Details for Tuberin

Target: Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

Alternative Name: Tuberin / TSC2

Background: Name/Gene ID: TSC2

Synonyms: TSC2, LAM, Tuberous sclerosis 2 protein, TSC4, Tuberin, Tuberous sclerosis 2

Gene ID: 7249

UniProt: P49815

Pathways: RTK Signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus