CD4 antibody
Quick Overview for CD4 antibody (ABIN1834899)
Target
See all CD4 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- Is a monoclonal antibody specific for the canine CD4 cell surface antigen. Clone YKIX302.9 was clustered at the first Canine Leukocyte Antigen Workshop (CLAW) [] along with clone CA13.1E4. Has been demonstrated to partially deplete circulating T lymphocytes when administered in vivo, but alone was not sufficient to prolong allograft survival in a canine transplant model. Uniquely amongst mammals, canine CD4 is expressed by neutrophils as well as by lymphocytes subsets. Forms part of a panel of anti canine monoclonal antibodies used extensively in the evaluation of leukemic status in dogs.
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Purification
- Protein G purified
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Immunogen
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Canine Concanavalin A activated T-cell blasts.
Type of Immunogen: Cells -
Isotype
- IgG2a
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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Target Species of Antibody: Dog
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C,-20 °C
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Storage Comment
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- CD4
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Alternative Name
- CD4
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Background
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Name/Gene ID: CD4
Synonyms: CD4, CD4 antigen, CD4 receptor, CD4mut, CD4 antigen (p55), CD4 Molecule -
Gene ID
- 920
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UniProt
- P01730
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Pathways
- TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
Target
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