Osteopontin antibody (AA 167-314)

Catalog No. ABIN1845756

The Mouse Monoclonal anti-Osteopontin antibody (ABIN1845756) specifically detects Osteopontin in WB, IHC, ELISA and IF/ICC. The antibody is reactive with Human samples.

Quick Overview for Osteopontin antibody (AA 167-314) (ABIN1845756)

Target: Osteopontin (SPP1) (Secreted phosphoprotein 1 (SPP1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Osteopontin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (fixed cells) (IF/ICC)

Product Details anti-Osteopontin Antibody

Binding Specificity: AA 167-314

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human SPP1 (AA: 167-314) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.

Target Details for Osteopontin

Target: Osteopontin (SPP1) (Secreted phosphoprotein 1 (SPP1))

Alternative Name: SPP1

Background: The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 35.4 kDa

Gene ID: 6696

UniProt: P10451

Pathways: Regulation of Cell Size