Surfactant Protein C antibody (AA 60-180)

Catalog No. ABIN1846306

This Mouse Monoclonal antibody specifically detects Surfactant Protein C in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for Surfactant Protein C antibody (AA 60-180) (ABIN1846306)

Target: Surfactant Protein C (SFTPC)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Surfactant Protein C antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Surfactant Protein C Antibody

Binding Specificity: AA 60-180

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human SFTPC (AA: 60-180) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.

Target Details for Surfactant Protein C

Target: Surfactant Protein C (SFTPC)

Alternative Name: SFTPC

Background: This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults.

Molecular Weight: 21 kDa

Gene ID: 6440

UniProt: P11686