NGFR antibody (Internal Region)

Catalog No. ABIN185411

The Goat Polyclonal anti-NGFR antibody is suitable to detect NGFR in samples from Human. It has been validated for WB and ELISA.

Quick Overview for NGFR antibody (Internal Region) (ABIN185411)

Target: NGFR (Nerve Growth Factor Receptor (NGFR))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This NGFR antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Verified

Product Details anti-NGFR Antibody

Binding Specificity: Internal Region

Purpose: NGFR

Sequence: AKREEVEKLL NG

Cross-Reactivity: Cow, Dog, Human, Mouse, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-AKREEVEKLLNG, from the internal region of the protein sequence according to NP_002498.1.

Isotype: IgG

Application Details

Application Notes:

Western Blot: Approx 75 kDa band observed in Human Duodenum and Human Heart lysates (calculated MW of 45.2 kDa according to NP_4804). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Nykjaer et al, Cur

Peptide ELISA: antibody detection limit dilution 1:32000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for NGFR

Target: NGFR (Nerve Growth Factor Receptor (NGFR))

Alternative Name: NGFR

Background: NGFR, nerve growth factor receptor (TNFR superfamily, member 16) , HGNC:7809, TNFRSF16, p75(NTR), p75NTR, CD271, Gp80-LNGFR, low affinity nerve growth factor receptor, low-affinity nerve growth factor receptor, nerve growth factor receptor

Gene ID: 4804

NCBI Accession: NP_002498

Pathways: NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding