HVEM antibody (Internal Region)

Catalog No. ABIN185517

Product Details anti-HVEM Antibody

Target: HVEM (TNFRSF14) (Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14))

Binding Specificity: Internal Region

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This HVEM antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purpose: HVEM / TR2

Sequence: SVQRKRQEAE GE

Cross-Reactivity: Human

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Grade: Verified

Immunogen: Peptide with sequence C-SVQRKRQEAEGE, from the internal region of the protein sequence according to NP_003811.2.

Isotype: IgG

Application Details

Application Notes:

Immunohistochemistry: Paraffin embedded Human Kidney. Recommended concentration: 5 μg/mL.

Western Blot: Approx 30 kDa band observed in Human Thymus and Tonsil lysates (calculated MW of 30.4 kDa according to NP_003811.2). Recommended concentration: 0.03-0.1 μg/mL.

Peptide ELISA: antibody detection limit dilution 1:32000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for HVEM

Target: HVEM (TNFRSF14) (Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14))

Alternative Name: TNFRSF14 (TNFRSF14 Products)

Target Type: Viral Protein

Background: TNFRSF14, HVEM, TR2, tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator), HGNC:11912, ATAR, HVEA, LIGHTR, CD40-like protein precursor, herpesvirus entry mediator, herpesvirus entry mediator A, tumor necrosis factor receptor

Gene ID: 8764

NCBI Accession: NP_003811

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints