5HT1B Receptor antibody (C-Term)

Catalog No. ABIN185637

This anti-5HT1B Receptor antibody is a Goat Polyclonal antibody detecting 5HT1B Receptor in WB and ELISA. Suitable for Human and Mouse.

Quick Overview for 5HT1B Receptor antibody (C-Term) (ABIN185637)

Target: 5HT1B Receptor (HTR1B) (Serotonin Receptor 1B (HTR1B))

Reactivity: Human, Mouse

Host: Goat

Clonality: Polyclonal

Conjugate: This 5HT1B Receptor antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Verified

Product Details anti-5HT1B Receptor Antibody

Binding Specificity: C-Term

Purpose: Serotonin receptor 1B / HTR1B

Sequence: SNEDFKQAFH K

Cross-Reactivity: Cat, Cow, Dog, Human, Mouse, Pig, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-SNEDFKQAFHK, from the C Terminus of the protein sequence according to NP_000854.1.

Isotype: IgG

Application Details

Application Notes:

Western Blot: Approx 48 kDa band observed in Human Brain (Cerebellum) and 48+45 kDa band observed in Mouse Spinal Cord lysates (calculated MW of 43.6 kDa according to NP_000854.1). Recommended concentration: 1-3 μg/mL. Primary incubation was 1 hour.

Peptide ELISA: antibody detection limit dilution 1:128000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for 5HT1B Receptor

Target: 5HT1B Receptor (HTR1B) (Serotonin Receptor 1B (HTR1B))

Alternative Name: HTR1B

Background: HTR1B, 5-hydroxytryptamine (serotonin) receptor 1B, 5-HT1B, 5-HT1DB, HTR1D2, HTR1DB, S12

Gene ID: 3351, 15551, 25075

NCBI Accession: NP_000854

Pathways: JAK-STAT Signaling, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, S100 Proteins