ABCB4 antibody

Catalog No. ABIN187326

The Mouse Monoclonal anti-ABCB4 antibody (Clone P3II-26) (ABIN187326) specifically detects ABCB4 in WB, IF and IHC (fro). The antibody is reactive with Human samples.

Quick Overview for ABCB4 antibody (ABIN187326)

Target: ABCB4 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ABCB4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: P3II-26

Product Details anti-ABCB4 Antibody

Specificity: P3II26 reacts with an internal epitope of MDR3 P-gp. P3II-26 does not cross-react with the human MDR1 p-Glycoprotein. Species Reactivity: Human and guinea pig. Others not tested.

Isotype: IgG2b

Application Details

Application Notes: Western blotting: The Mab is reactive in Western blots. Immunocytochemistry: Use at a dilution of 1:20-50 on acetone fixed cytospin preparations. Immunohistochemistry: Use 1:20 on acetone fixed frozen sections can be followed by incubation with rabbit anti-mouse IgG and a monoclonal mouse APAAP complex. P3II-26 does not work very well on formaldehyde-fixed paraffin-embedded human tissues. Flow Cytometry: Optimal conditions still to be defined. The optimal dilution for a specific application should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.5 ml vial containing antibody in serum-free culture supernatant, with 0.7% BSA and 0.1% Sodium azide. Concentration approx. 500 µg immunoglobulin/ml.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for ABCB4

Target: ABCB4 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4))

Alternative Name: ABCB4 / MDR3

Pathways: Regulation of Lipid Metabolism by PPARalpha