COPG antibody (C-Term)

Catalog No. ABIN1881223

This Rabbit Polyclonal antibody specifically detects COPG in WB. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for COPG antibody (C-Term) (ABIN1881223)

Target: COPG (Coatomer Protein Complex, Subunit gamma (COPG))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COPG antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB41787

Product Details anti-COPG Antibody

Binding Specificity: AA 721-750, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This COPG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 721-750 amino acids from the C-terminal region of human COPG.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-COPG antibody (ABIN1881223)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Rohde, Cheong, Konrad, Paiha, Mayinger, Boehmelt: "The human phosphatidylinositol phosphatase SAC1 interacts with the coatomer I complex." in: The Journal of biological chemistry, Vol. 278, Issue 52, pp. 52689-99, (2003) (PubMed).

Target Details for COPG

Target: COPG (Coatomer Protein Complex, Subunit gamma (COPG))

Alternative Name: COPG

Background: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins, the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity).

Molecular Weight: 97718

NCBI Accession: NP_057212

UniProt: Q9Y678