COPG antibody

Catalog No. ABIN7228022

This Rabbit Polyclonal antibody specifically detects COPG in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for COPG antibody (ABIN7228022)

Target: COPG (Coatomer Protein Complex, Subunit gamma (COPG))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COPG antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-COPG Antibody

Purpose: Rabbit Anti-COPG1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of COPG1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human COPG1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for COPG

Target: COPG (Coatomer Protein Complex, Subunit gamma (COPG))

Alternative Name: COPG1

Background: Coatomer subunit gamma-1, Gamma-1-coat protein, Gamma-1-COPCOPG1 (Coatomer Protein Complex Subunit Gamma 1) is a Protein Coding gene. Among its related pathways are wtCFTR and delta508-CFTR traffic/Generic schema (norm and CF) and Golgi-to-ER retrograde transport. The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Required for limiting lipid storage in lipid droplets. Involved in lipid homeostasis by regulating the presence of perilipin family members PLIN2 and PLIN3 at the lipid droplet surface and promoting the association of adipocyte triglyceride lipase (PNPLA2) with the lipid droplet surface to mediate lipolysis (By similarity).

Molecular Weight: 96kD

Gene ID: 22820

UniProt: Q9Y678