COPG antibody (AA 555-874)

Catalog No. ABIN6138875

Product Details anti-COPG Antibody

Target: COPG (Coatomer Protein Complex, Subunit gamma (COPG))

Binding Specificity: AA 555-874

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COPG antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: IPGLERALQQ YTLEPSEKPF DLKSVPLATA PMAEQRTEST PITAVKQPEK VAATRQEIFQ EQLAAVPEFR GLGPLFKSSP EPVALTESET EYVIRCTKHT FTNHMVFQFD CTNTLNDQTL ENVTVQMEPT EAYEVLCYVP ARSLPYNQPG TCYTLVALPK EDPTAVACTF SCMMKFTVKD CDPTTGETDD EGYEDEYVLE DLEVTVADHI QKVMKLNFEA AWDEVGDEFE KEETFTLSTI KTLEEAVGNI VKFLGMHPCE RSDKVPDNKN THTLLLAGVF RGGHDILVRS RLLLLDTVTM QVTARSLEEL PVDIILASVG

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 555-874 of human COPG1 (NP_057212.1).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:2000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for COPG

Target: COPG (Coatomer Protein Complex, Subunit gamma (COPG))

Alternative Name: COPG1 (COPG Products)

Synonyms: COPG antibody, COPG2 antibody, AU019265 antibody, BC056168 antibody, Copg antibody, D6Ertd71e antibody, D6Wsu16e antibody, copg1 antibody, MGC76032 antibody, MGC68533 antibody, COPG1 antibody, coatomer protein complex subunit gamma 1 antibody, coatomer protein complex, subunit gamma 1 antibody, coatomer protein complex subunit gamma 1 L homeolog antibody, coatomer subunit gamma-1 antibody, COPG1 antibody, Copg1 antibody, copg1 antibody, copg1.L antibody, LOC100050080 antibody

Background: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs, which are small GTP-binding proteins, the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors. Required for limiting lipid storage in lipid droplets. Involved in lipid homeostasis by regulating the presence of perilipin family members PLIN2 and PLIN3 at the lipid droplet surface and promoting the association of adipocyte triglyceride lipase (PNPLA2 with the lipid droplet surface to mediate lipolysis (By similarity.,COPG1,COPG,Signal Transduction,COPG1

Molecular Weight: 97 kDa

Gene ID: 22820

UniProt: Q9Y678