FGF8 antibody (N-Term)

Catalog No. ABIN1881345

Product Details anti-FGF8 Antibody

Target: FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))

Binding Specificity: AA 30-59, N-Term

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGF8 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Fgf8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-59 amino acids from the N-terminal region of mouse Fgf8.

Clone: RB40263

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-FGF8 antibody (ABIN1881345)

Fleming, Quan, Wang, Amit, Rollins: "In vitro characterization of cardiac radiofrequency ablation lesions using optical coherence tomography." in: Optics express, Vol. 18, Issue 3, pp. 3079-92, (2010) (PubMed).

Yu, Poe, Schwarz, Elliot, Albertine, Fenton, Garg, Moon: "Fetal and postnatal lung defects reveal a novel and required role for Fgf8 in lung development." in: Developmental biology, Vol. 347, Issue 1, pp. 92-108, (2010) (PubMed).

Toyoda, Assimacopoulos, Wilcoxon, Taylor, Feldman, Suzuki-Hirano, Shimogori, Grove: "FGF8 acts as a classic diffusible morphogen to pattern the neocortex." in: Development (Cambridge, England), Vol. 137, Issue 20, pp. 3439-48, (2010) (PubMed).

Leung, Wong, Chan, Tam, Cheah: "Loss of procollagen IIA from the anterior mesendoderm disrupts the development of mouse embryonic forebrain." in: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 239, Issue 9, pp. 2319-29, (2010) (PubMed).

Mitsiadis, Graf, Luder, Gridley, Bluteau: "BMPs and FGFs target Notch signalling via jagged 2 to regulate tooth morphogenesis and cytodifferentiation." in: Development (Cambridge, England), Vol. 137, Issue 18, pp. 3025-35, (2010) (PubMed).

Target Details for FGF8

Target: FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))

Alternative Name: Fgf8 (FGF8 Products)

Synonyms: Aigf antibody, Fgf-8 antibody, AIGF antibody, FGF-8 antibody, HBGF-8 antibody, HH6 antibody, KAL6 antibody, fibroblast growth factor 8 antibody, Fgf8 antibody, FGF8 antibody

Background: Stimulates growth of the cells in an autocrine manner. Mediates hormonal action on the growth of cancer cells. Cooperates with Wnt-1 in mouse mammary tumor virus-induced murine mammary tumorigenesis.

Molecular Weight: 30420

NCBI Accession: NP_001159834, NP_001159835, NP_034335

UniProt: P37237

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Dopaminergic Neurogenesis