ILF2 antibody (N-Term)

Catalog No. ABIN1881458

There are 5+ publications for this product available. The Rabbit Polyclonal anti-ILF2 antibody is suitable to detect ILF2 in samples from Human. It has been validated for WB.

Quick Overview for ILF2 antibody (N-Term) (ABIN1881458)

Target: ILF2 (Interleukin Enhancer Binding Factor 2, 45kDa (ILF2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ILF2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB42341

Product Details anti-ILF2 Antibody

Binding Specificity: AA 84-112, N-Term

Predicted Reactivity: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ILF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 84-112 amino acids from the N-terminal region of human ILF2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-ILF2 antibody (ABIN1881458)

Karmakar, Mahajan, Schulz, Boyapaty, Weissman: "A multiprotein complex necessary for both transcription and DNA replication at the β-globin locus." in: The EMBO journal, Vol. 29, Issue 19, pp. 3260-71, (2010) (PubMed).

Graber, Baird, Kao, Mathews, Holcik: "NF45 functions as an IRES trans-acting factor that is required for translation of cIAP1 during the unfolded protein response." in: Cell death and differentiation, Vol. 17, Issue 4, pp. 719-29, (2010) (PubMed).

Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, (2010) (PubMed).

Kiesler, Haynes, Shi, Kao, Wysocki, Vercelli: "NF45 and NF90 regulate HS4-dependent interleukin-13 transcription in T cells." in: The Journal of biological chemistry, Vol. 285, Issue 11, pp. 8256-67, (2010) (PubMed).

Sakamoto, Aoki, Higuchi, Todaka, Morisawa, Tamaki, Hatano, Fukushima, Taniguchi, Agata: "The NF90-NF45 complex functions as a negative regulator in the microRNA processing pathway." in: Molecular and cellular biology, Vol. 29, Issue 13, pp. 3754-69, (2009) (PubMed).

Target Details for ILF2

Target: ILF2 (Interleukin Enhancer Binding Factor 2, 45kDa (ILF2))

Alternative Name: ILF2

Background: Nuclear factor of activated T-cells (NFAT) is a transcription factor required for T-cell expression of the interleukin 2 gene. NFAT binds to a sequence in the interleukin 2 gene enhancer known as the antigen receptor response element 2. In addition, NFAT can bind RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the smaller of which is the product of this gene. The encoded protein binds strongly to the 90 kDa protein and stimulates its ability to enhance gene expression.

Molecular Weight: 43062

NCBI Accession: NP_001254738, NP_004506

UniProt: Q12905