C-JUN antibody (AA 221-250)

Catalog No. ABIN1881471

This anti-C-JUN antibody is a Rabbit Polyclonal antibody detecting C-JUN in WB and IHC (p). Suitable for Human. This Primary Antibody has been cited in 3+ publications.

Quick Overview for C-JUN antibody (AA 221-250) (ABIN1881471)

Target: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C-JUN antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB11143

Product Details anti-C-JUN Antibody

Binding Specificity: AA 221-250

Predicted Reactivity: B, C, M, Pig, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This JUN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 221-250 amino acids from human JUN.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-C-JUN antibody (ABIN1881471)

Madhunapantula, Robertson: "Is B-Raf a good therapeutic target for melanoma and other malignancies?" in: Cancer research, Vol. 68, Issue 1, pp. 5-8, (2008) (PubMed).

Fujita, Ito, Mizutani, Minoguchi, Yamamichi, Sakurai, Iba: "miR-21 Gene expression triggered by AP-1 is sustained through a double-negative feedback mechanism." in: Journal of molecular biology, Vol. 378, Issue 3, pp. 492-504, (2008) (PubMed).

Gan, Wang, Xi, Wu, Li, Li: "Nuclear Dvl, c-Jun, beta-catenin, and TCF form a complex leading to stabilization of beta-catenin-TCF interaction." in: The Journal of cell biology, Vol. 180, Issue 6, pp. 1087-100, (2008) (PubMed).

Target Details for C-JUN

Target: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Alternative Name: JUN

Background: JUN interacts directly with specific target DNA sequences to regulate gene expression.

Molecular Weight: 35676

NCBI Accession: NP_002219

UniProt: P05412

Pathways: MAPK Signaling, RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteins