KHDRBS2 antibody (C-Term)

Catalog No. ABIN1881478

This Rabbit Polyclonal antibody specifically detects KHDRBS2 in WB. It exhibits reactivity toward Human and Rat. It has been mentioned in 3+ publications

Quick Overview for KHDRBS2 antibody (C-Term) (ABIN1881478)

Target: KHDRBS2 (KH Domain Containing, RNA Binding, Signal Transduction Associated 2 (KHDRBS2))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KHDRBS2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KHDRBS2 Antibody

Binding Specificity: AA 298-321, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This KHDRBS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 298-321 amino acids from the C-terminal region of human KHDRBS2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-KHDRBS2 antibody (ABIN1881478)

Wang, Xu, Zeng, Ye, Wu, Dai, Ji, Gu, Zhao, Xie, Mao: "Cloning and characterization of a novel human STAR domain containing cDNA KHDRBS2." in: Molecular biology reports, Vol. 29, Issue 4, pp. 369-75, (2003) (PubMed).

Côté, Boisvert, Boulanger, Bedford, Richard: "Sam68 RNA binding protein is an in vivo substrate for protein arginine N-methyltransferase 1." in: Molecular biology of the cell, Vol. 14, Issue 1, pp. 274-87, (2003) (PubMed).

Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: "The DNA sequence and analysis of human chromosome 6. ..." in: Nature, Vol. 425, Issue 6960, pp. 805-11, (2003) (PubMed).

Target Details for KHDRBS2

Target: KHDRBS2 (KH Domain Containing, RNA Binding, Signal Transduction Associated 2 (KHDRBS2))

Alternative Name: KHDRBS2

Background: RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. May function as an adapter protein for Src kinases during mitosis. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability (By similarity).

Molecular Weight: 38927

NCBI Accession: NP_689901

UniProt: Q5VWX1