KISS1R antibody (AA 270-350)

Catalog No. ABIN7225438

The Rabbit Polyclonal anti-KISS1R antibody is suitable to detect KISS1R in samples from Human, Rat and Mouse. It has been validated for IHC, ELISA and IF.

Quick Overview for KISS1R antibody (AA 270-350) (ABIN7225438)

Target: KISS1R (KISS1 Receptor (KISS1R))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KISS1R antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-KISS1R Antibody

Binding Specificity: AA 270-350

Purpose: Rabbit Anti-KiSS-1R Polyclonal Antibody

Specificity: KiSS-1R Polyclonal Antibody detects endogenous levels of KiSS-1R protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human KiSS-1R at AA range: 270-350

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,IF 1:100-1:500,ELISA 1:5000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for KISS1R

Target: KISS1R (KISS1 Receptor (KISS1R))

Alternative Name: KiSS-1R

Background: KISS1R, AXOR12, GPR54, KiSS-1 receptor, KiSS-1R, G-protein coupled receptor 54, G-protein coupled receptor OT7T175, hOT7T175, Hypogonadotropin-1, Kisspeptins receptor, Metastin receptorThe protein encoded by KISS1R (KISS1 receptor) is a galanin-like G protein-coupled receptor that binds metastin, a peptide encoded by the metastasis suppressor gene KISS1. The tissue distribution of the expressed gene suggests that it is involved in the regulation of endocrine function, and this is supported by the finding that this gene appears to play a role in the onset of puberty. Mutations in KISS1R have been associated with hypogonadotropic hypogonadism and central precocious puberty.

Gene ID: 84634

UniProt: Q969F8