NIFK antibody (C-Term)

Catalog No. ABIN1881542

There are 3+ publications for this product available. The Rabbit Polyclonal anti-NIFK antibody is suitable to detect NIFK in samples from Human. It has been validated for WB.

Quick Overview for NIFK antibody (C-Term) (ABIN1881542)

Target: NIFK (MKI67IP) (MKI67 FHA Domain-Interacting Nucleolar Phosphoprotein (MKI67IP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NIFK antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB41688

Product Details anti-NIFK Antibody

Binding Specificity: AA 232-260, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MKI67IP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-260 amino acids from the C-terminal region of human MKI67IP.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-NIFK antibody (ABIN1881542)

Byeon, Li, Song, Gronenborn, Tsai: "Sequential phosphorylation and multisite interactions characterize specific target recognition by the FHA domain of Ki67." in: Nature structural & molecular biology, Vol. 12, Issue 11, pp. 987-93, (2006) (PubMed).

Li, Byeon, Ju, Tsai: "Structure of human Ki67 FHA domain and its binding to a phosphoprotein fragment from hNIFK reveal unique recognition sites and new views to the structural basis of FHA domain functions." in: Journal of molecular biology, Vol. 335, Issue 1, pp. 371-81, (2003) (PubMed).

Takagi, Sueishi, Saiwaki, Kametaka, Yoneda: "A novel nucleolar protein, NIFK, interacts with the forkhead associated domain of Ki-67 antigen in mitosis." in: The Journal of biological chemistry, Vol. 276, Issue 27, pp. 25386-91, (2001) (PubMed).

Target Details for NIFK

Target: NIFK (MKI67IP) (MKI67 FHA Domain-Interacting Nucleolar Phosphoprotein (MKI67IP))

Alternative Name: MKI67IP

Background: This gene encodes a protein that interacts with the forkhead-associated domain of the Ki-67 antigen. The encoded protein may bind RNA and may play a role in mitosis and cell cycle progression. Multiple pseudogenes exist on chromosomes 5, 10, 12, 15, and 19.

Molecular Weight: 34222

NCBI Accession: NP_115766

UniProt: Q9BYG3