NFE2L3 antibody (AA 460-540)

Catalog No. ABIN7216134

This Rabbit Polyclonal antibody specifically detects NFE2L3 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for NFE2L3 antibody (AA 460-540) (ABIN7216134)

Target: NFE2L3 (Nuclear Factor (erythroid-Derived 2)-Like 3 (NFE2L3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFE2L3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-NFE2L3 Antibody

Binding Specificity: AA 460-540

Purpose: Rabbit Anti-Nrf3 Polyclonal Antibody

Specificity: Nrf3 Polyclonal Antibody detects endogenous levels of Nrf3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Nrf3 at AA range: 460-540

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NFE2L3

Target: NFE2L3 (Nuclear Factor (erythroid-Derived 2)-Like 3 (NFE2L3))

Alternative Name: Nrf3

Background: NFE2L3, NRF3, Nuclear factor erythroid 2-related factor 3, NF-E2-related factor 3, NFE2-related factor 3, Nuclear factor, erythroid derived 2, like 3NFE2L3 encodes a member of the cap 'n' collar basic-region leucine zipper family of transcription factors. Nuclear factor, erythroid 2 like 3 heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. Nuclear factor, erythroid 2 like 3 is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of NFE2L3 are found on chromosomes 16, 17, and 18.

Molecular Weight: 75kD

Gene ID: 9603

UniProt: Q9Y4A8