PDCD6 antibody (N-Term)

Catalog No. ABIN1881643

Product Details anti-PDCD6 Antibody

Target: PDCD6 (Programmed Cell Death 6 (PDCD6))

Binding Specificity: AA 19-47, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDCD6 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PDCD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-47 amino acids from the N-terminal region of human PDCD6.

Clone: RB41816

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-PDCD6 antibody (ABIN1881643)

Vergarajauregui, Martina, Puertollano: "Identification of the penta-EF-hand protein ALG-2 as a Ca2+-dependent interactor of mucolipin-1." in: The Journal of biological chemistry, Vol. 284, Issue 52, pp. 36357-66, (2009) (PubMed).

Okumura, Ichioka, Kobayashi, Suzuki, Yoshida, Shibata, Maki: "Penta-EF-hand protein ALG-2 functions as a Ca2+-dependent adaptor that bridges Alix and TSG101." in: Biochemical and biophysical research communications, Vol. 386, Issue 1, pp. 237-41, (2009) (PubMed).

Abe, Miyakushi, Nagai, Norimatsu: "Study of the factors affecting the photoelectrode characteristics of a perylene/phthalocyanine bilayer working in the water phase." in: Physical chemistry chemical physics : PCCP, Vol. 10, Issue 11, pp. 1562-8, (2008) (PubMed).

Yamada, Arao, Gotoda, Taniguchi, Oda, Shirao, Shimada, Hamaguchi, Kato, Hamano, Koizumi, Tamura, Saito, Shimoda, Saka, Fukagawa, Katai, Sano, Sasako, Nishio: "Identification of prognostic biomarkers in gastric cancer using endoscopic biopsy samples." in: Cancer science, Vol. 99, Issue 11, pp. 2193-9, (2008) (PubMed).

Target Details for PDCD6

Target: PDCD6 (Programmed Cell Death 6 (PDCD6))

Alternative Name: PDCD6 (PDCD6 Products)

Synonyms: pdcd6 antibody, MGC52821 antibody, MGC132114 antibody, zgc:63952 antibody, PDCD6 antibody, ALG-2 antibody, PEF1B antibody, AV299538 antibody, Alg2 antibody, MA-3 antibody, PS2 antibody, alg-2 antibody, programmed cell death 6 L homeolog antibody, programmed cell death 6 antibody, pdcd6.L antibody, pdcd6 antibody, PDCD6 antibody, Pdcd6 antibody

Background: This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant.

Molecular Weight: 21868

NCBI Accession: NP_001254485, NP_001254486, NP_001254487, NP_001254488, NP_037364

UniProt: O75340

Pathways: Positive Regulation of Endopeptidase Activity