PDCD6 antibody

Catalog No. ABIN7240187

The Rabbit Polyclonal anti-PDCD6 antibody (ABIN7240187) specifically detects PDCD6 in WB, ELISA and IHC. The antibody is reactive with Human and Mouse samples.

Quick Overview for PDCD6 antibody (ABIN7240187)

Target: PDCD6 (Programmed Cell Death 6 (PDCD6))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDCD6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PDCD6 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human PDCD6

Isotype: IgG

Application Details

Application Notes: WB 1:200-1:1000, IHC 1:25-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PDCD6

Target: PDCD6 (Programmed Cell Death 6 (PDCD6))

Alternative Name: PDCD6

Background: This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5.

Molecular Weight: 22 kDa

UniProt: O75340

Pathways: Positive Regulation of Endopeptidase Activity