POLD2 antibody (AA 237-265)

Catalog No. ABIN1881666

Cited in 4+ publications. The Rabbit Polyclonal anti-POLD2 antibody (Clone RB46018) (ABIN1881666) specifically detects POLD2 in WB. The antibody is reactive with Human and Rat samples.

Quick Overview for POLD2 antibody (AA 237-265) (ABIN1881666)

Target: POLD2 (Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLD2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB46018

Product Details anti-POLD2 Antibody

Binding Specificity: AA 237-265

Predicted Reactivity: B, M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This POLD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 237-265 amino acids from the Central region of human POLD2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-POLD2 antibody (ABIN1881666)

Tsurimoto, Shinozaki, Yano, Seki, Enomoto: "Human Werner helicase interacting protein 1 (WRNIP1) functions as a novel modulator for DNA polymerase delta." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 10, Issue 1, pp. 13-22, (2005) (PubMed).

He, Tan, Downey, So: "A tumor necrosis factor alpha- and interleukin 6-inducible protein that interacts with the small subunit of DNA polymerase delta and proliferating cell nuclear antigen." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 21, pp. 11979-84, (2001) (PubMed).

Perez, Leon, Lee: "Characterization of the 5'-flanking region of the gene encoding the 50 kDa subunit of human DNA polymerase delta." in: Biochimica et biophysica acta, Vol. 1493, Issue 1-2, pp. 231-6, (2000) (PubMed).

Zhang, Tan, McMullen, Downey, So: "Cloning of the cDNAs for the small subunits of bovine and human DNA polymerase delta and chromosomal location of the human gene (POLD2)." in: Genomics, Vol. 29, Issue 1, pp. 179-86, (1996) (PubMed).

Target Details for POLD2

Target: POLD2 (Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2))

Alternative Name: POLD2

Background: The function of the small subunit is not yet clear.

Molecular Weight: 51289

NCBI Accession: NP_001120690, NP_001243808, NP_006221

UniProt: P49005

Pathways: Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA