POLD2 antibody (AA 120-360)

Catalog No. ABIN6145879

Product Details anti-POLD2 Antibody

Target: POLD2 (Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2))

Binding Specificity: AA 120-360

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLD2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LQPEEKCCVV GTLFKAMPLQ PSILREVSEE HNLLPQPPRS KYIHPDDELV LEDELQRIKL KGTIDVSKLV TGTVLAVFGS VRDDGKFLVE DYCFADLAPQ KPAPPLDTDR FVLLVSGLGL GGGGGESLLG TQLLVDVVTG QLGDEGEQCS AAHVSRVILA GNLLSHSTQS RDSINKAKYL TKKTQAASVE AVKMLDEILL QLSASVPVDV MPGEFDPTNY TLPQQPLHPC MFPLATAYST L

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 120-360 of human POLD2 (NP_006221.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for POLD2

Target: POLD2 (Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2))

Alternative Name: POLD2 (POLD2 Products)

Synonyms: 50kDa antibody, p50 antibody, po1D2 antibody, cdc1 antibody, si:dz150f13.3 antibody, zgc:55633 antibody, zgc:77043 antibody, DNA polymerase delta 2, accessory subunit antibody, polymerase (DNA directed), delta 2, regulatory subunit antibody, polymerase (DNA directed), delta 2, accessory subunit L homeolog antibody, POLD2 antibody, Pold2 antibody, pold2.L antibody, pold2 antibody

Background: This gene encodes the 50- kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA). Expression of this gene may be a marker for ovarian carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5.,POLD2,Epigenetics & Nuclear Signaling,POLD2

Molecular Weight: 51 kDa

Gene ID: 5425

UniProt: P49005

Pathways: Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA