POLR2G antibody (C-Term)

Catalog No. ABIN1881671

There are 4+ publications for this product available. The Rabbit Polyclonal anti-POLR2G antibody is suitable to detect POLR2G in samples from Human. It has been validated for WB.

Quick Overview for POLR2G antibody (C-Term) (ABIN1881671)

Target: POLR2G (Polymerase (RNA) II (DNA Directed) Polypeptide G (POLR2G))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLR2G antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB42404

Product Details anti-POLR2G Antibody

Binding Specificity: AA 125-154, C-Term

Predicted Reactivity: B, Zf, M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This POLR2G antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 125-154 amino acids from the C-terminal region of human POLR2G.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-POLR2G antibody (ABIN1881671)

Cojocaru, Jeronimo, Forget, Bouchard, Bergeron, Côte, Poirier, Greenblatt, Coulombe: "Genomic location of the human RNA polymerase II general machinery: evidence for a role of TFIIF and Rpb7 at both early and late stages of transcription." in: The Biochemical journal, Vol. 409, Issue 1, pp. 139-47, (2007) (PubMed).

Ujvári, Luse: "RNA emerging from the active site of RNA polymerase II interacts with the Rpb7 subunit." in: Nature structural & molecular biology, Vol. 13, Issue 1, pp. 49-54, (2006) (PubMed).

Meka, Werner, Cordell, Onesti, Brick: "Crystal structure and RNA binding of the Rpb4/Rpb7 subunits of human RNA polymerase II." in: Nucleic acids research, Vol. 33, Issue 19, pp. 6435-44, (2005) (PubMed).

Zhou, Deng, Kashanchi, Brady, Shatkin, Kumar: "The Tat/TAR-dependent phosphorylation of RNA polymerase II C-terminal domain stimulates cotranscriptional capping of HIV-1 mRNA." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 22, pp. 12666-71, (2003) (PubMed).

Target Details for POLR2G

Target: POLR2G (Polymerase (RNA) II (DNA Directed) Polypeptide G (POLR2G))

Alternative Name: POLR2G

Background: This gene encodes the seventh largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The protein functions in transcription initiation, and is also thought to help stabilize transcribing polyermase molecules during elongation.

Molecular Weight: 19294

NCBI Accession: NP_002687

UniProt: P62487

Pathways: Regulatory RNA Pathways