POLR2G antibody (AA 1-172)

Catalog No. ABIN7150438

Product Details anti-POLR2G Antibody

Target: POLR2G (Polymerase (RNA) II (DNA Directed) Polypeptide G (POLR2G))

Binding Specificity: AA 1-172

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLR2G antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human DNA-directed RNA polymerase II subunit RPB7 protein (1-172AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for POLR2G

Target: POLR2G (Polymerase (RNA) II (DNA Directed) Polypeptide G (POLR2G))

Alternative Name: POLR2G (POLR2G Products)

Synonyms: RPB19 antibody, RPB7 antibody, hRPB19 antibody, hsRPB7 antibody, Rpb7 antibody, POLR2G antibody, 2410046K11Rik antibody, A230108L04Rik antibody, C76415 antibody, RBP7 antibody, Rpo2-7l antibody, RNA polymerase II subunit G antibody, polymerase (RNA) II (DNA directed) polypeptide G antibody, polymerase (RNA) II (DNA directed) polypeptide G L homeolog antibody, POLR2G antibody, Polr2g antibody, polr2g antibody, polr2g.L antibody

Background:

Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA (By similarity). Binds RNA.

Aliases: DNA directed RNA polymerase II 19 kDa polypeptide antibody, DNA directed RNA polymerase II subunit G antibody, DNA directed RNA polymerase II subunit RPB7 antibody, DNA-directed RNA polymerase II subunit G antibody, DNA-directed RNA polymerase II subunit RPB7 antibody, hRPB19 antibody, hsRPB7 antibody, MGC138367 antibody, MGC138369 antibody, POLR2G antibody, polymerase (RNA) II (DNA directed) polypeptide G antibody, RNA polymerase II 19 kDa subunit antibody, RNA polymerase II subunit B7 antibody, RPB19 antibody, RPB7 antibody, RPB7_HUMAN antibody

UniProt: P62487

Pathways: Regulatory RNA Pathways