POLR2G antibody

Catalog No. ABIN7231150

This Rabbit Polyclonal antibody specifically detects POLR2G in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for POLR2G antibody (ABIN7231150)

Target: POLR2G (Polymerase (RNA) II (DNA Directed) Polypeptide G (POLR2G))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLR2G antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-POLR2G Antibody

Purpose: Rabbit Anti-RPB7 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of RPB7 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human RPB7 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for POLR2G

Target: POLR2G (Polymerase (RNA) II (DNA Directed) Polypeptide G (POLR2G))

Alternative Name: RPB7

Background: DNA-directed RNA polymerase II subunit RPB7, DNA-directed RNA polymerase II subunit G, RNA polymerase II 19 kDa subunitPOLR2G encodes the seventh largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The protein functions in transcription initiation, and is also thought to help stabilize transcribing polyermase molecules during elongation. POLR2G (RNA Polymerase II Subunit G) is a Protein Coding gene. Diseases associated with POLR2G include Myasthenic Syndrome, Congenital, 5 and Congenital Myasthenic Syndrome. Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and DNA damage_Role of Brca1 and Brca2 in DNA repair.

Molecular Weight: 18kD

Gene ID: 5436

UniProt: P62487

Pathways: Regulatory RNA Pathways