RAB8A antibody

Catalog No. ABIN1881723

This anti-RAB8A antibody is a Rabbit Polyclonal antibody detecting RAB8A in WB, IHC (p) and FACS. Suitable for Human. This Primary Antibody has been cited in 2+ publications.

Quick Overview for RAB8A antibody (ABIN1881723)

Target: RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB8A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: RB22933

Product Details anti-RAB8A Antibody

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RAB8A antibody is generated from rabbits immunized with human RAB8A recombinant protein.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-RAB8A antibody (ABIN1881723)

Rosas, Gabler, Vantman, Romero, Vega: "Levels of Rabs and WAVE family proteins associated with translocation of GLUT4 to the cell surface in endometria from hyperinsulinemic PCOS women." in: Human reproduction (Oxford, England), Vol. 25, Issue 11, pp. 2870-7, (2010) (PubMed).

Kato, Sekine, Oh, Kim, Umezawa, Abe, Yokoyama-Kobayashi, Aoki: "Construction of a human full-length cDNA bank." in: Gene, Vol. 150, Issue 2, pp. 243-50, (1995) (PubMed).

Target Details for RAB8A

Target: RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))

Alternative Name: RAB8A

Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. Anessential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. RAB8A is a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome.

Molecular Weight: 23668

NCBI Accession: NP_005361

UniProt: P61006

Pathways: M Phase, Regulation of long-term Neuronal Synaptic Plasticity, SARS-CoV-2 Protein Interactome