XRCC2 antibody (N-Term)

Catalog No. ABIN1882001

There are 3+ publications for this product available. The Rabbit Polyclonal anti-XRCC2 antibody is suitable to detect XRCC2 in samples from Human. It has been validated for WB.

Quick Overview for XRCC2 antibody (N-Term) (ABIN1882001)

Target: XRCC2 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 2 (XRCC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This XRCC2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB30583

Product Details anti-XRCC2 Antibody

Binding Specificity: AA 1-30, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This XRCC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human XRCC2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-XRCC2 antibody (ABIN1882001)

Schwarz, Daley, Beckhaus, Dötsch, Bernhard: "Cell-free expression profiling of E. coli inner membrane proteins." in: Proteomics, Vol. 10, Issue 9, pp. 1762-79, (2010) (PubMed).

Briggs, Goldstein, McCauley, Zuvich, De Jager, Rioux, Ivinson, Compston, Hafler, Hauser, Oksenberg, Sawcer, Pericak-Vance, Haines, Barcellos: "Variation within DNA repair pathway genes and risk of multiple sclerosis." in: American journal of epidemiology, Vol. 172, Issue 2, pp. 217-24, (2010) (PubMed).

Liu, Wu, Chen, Ter-Minassian, Asomaning, Zhai, Wang, Su, Heist, Kulke, Lin, Liu, Christiani: "A Large-scale genetic association study of esophageal adenocarcinoma risk." in: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, (2010) (PubMed).

Target Details for XRCC2

Target: XRCC2 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 2 (XRCC2))

Alternative Name: XRCC2

Background: This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene is involved in the repair of DNA double-strand breaks by homologous recombination and it functionally complements Chinese hamster irs1, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents.

Molecular Weight: 31956

NCBI Accession: NP_005422

UniProt: O43543

Pathways: DNA Damage Repair