IL1RN antibody (C-Term)

Catalog No. ABIN1882098

Cited in 1 publication. The Rabbit Polyclonal anti-IL1RN antibody (Clone RB18902) (ABIN1882098) specifically detects IL1RN in WB, IF and FACS. The antibody is reactive with Human samples.

Quick Overview for IL1RN antibody (C-Term) (ABIN1882098)

Target: IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL1RN antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: RB18902

Product Details anti-IL1RN Antibody

Binding Specificity: AA 147-177, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This IL1RN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-177 amino acids from the C-terminal region of human IL1RN.

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. WB: 1:4000. WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-IL1RN antibody (ABIN1882098)

Kumar, Kumar, Dixit: "Evidences showing association of interleukin-1B polymorphisms with increased risk of gastric cancer in an Indian population." in: Biochemical and biophysical research communications, Vol. 387, Issue 3, pp. 456-60, (2009) (PubMed).

Target Details for IL1RN

Target: IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))

Alternative Name: IL1RN

Background: The protein is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. A polymorphism of its gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer.

Molecular Weight: 20055

NCBI Accession: NP_000568, NP_776213, NP_776214, NP_776215

UniProt: P18510

Pathways: NF-kappaB Signaling, Hormone Transport, Cancer Immune Checkpoints