ERCC1 antibody (C-Term)

Catalog No. ABIN1882194

Cited in 3+ publications. The Mouse Monoclonal anti-ERCC1 antibody (Clone 752CT13-2-5) (ABIN1882194) specifically detects ERCC1 in WB. The antibody is reactive with Human samples.

Quick Overview for ERCC1 antibody (C-Term) (ABIN1882194)

Target: ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ERCC1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 752CT13-2-5

Product Details anti-ERCC1 Antibody

Binding Specificity: AA 268-297, C-Term

Purification: This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.

Immunogen: This ERCC1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 268-297 amino acids from the C-terminal region of human ERCC1.

Isotype: IgM kappa

Application Details

Application Notes: WB: 1:2000. WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-ERCC1 antibody (ABIN1882194)

Yu, Mu, Lee, Okamoto, Reed, Bostick-Bruton, Mitchell, Reed: "A nucleotide polymorphism in ERCC1 in human ovarian cancer cell lines and tumor tissues." in: Mutation research, Vol. 382, Issue 1-2, pp. 13-20, (1997) (PubMed).

Hoeijmakers, van Duin, Westerveld, Yasui, Bootsma: "Identification of DNA repair genes in the human genome." in: Cold Spring Harbor symposia on quantitative biology, Vol. 51 Pt 1, pp. 91-101, (1987) (PubMed).

van Duin, de Wit, Odijk, Westerveld, Yasui, Koken, Hoeijmakers, Bootsma: "Molecular characterization of the human excision repair gene ERCC-1: cDNA cloning and amino acid homology with the yeast DNA repair gene RAD10." in: Cell, Vol. 44, Issue 6, pp. 913-23, (1986) (PubMed).

Target Details for ERCC1

Target: ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))

Alternative Name: ERCC1

Background: Structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair.

Molecular Weight: 32562

NCBI Accession: NP_001159521, NP_001974, NP_973730

UniProt: P07992

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response