OTUB1 antibody (AA 1-119)
Quick Overview for OTUB1 antibody (AA 1-119) (ABIN1885581)
Target
See all OTUB1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-119
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Purification
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 119 of Human OTUB1
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Application Notes
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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Preservative
- Thimerosal (Merthiolate)
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Precaution of Use
- Biohazard Informations: This product contains thimerosal which is hazardous.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- OTUB1 (OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1))
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Alternative Name
- OTUB1
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Background
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The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases.The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates.It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system.It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth.Alternative splicing results in multiple transcript variants.[provided by RefSeq]
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Molecular Weight
- 31 kDa
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Gene ID
- 55611
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NCBI Accession
- NM_017670, NP_060140
Target
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