SOCS5 antibody (AA 1-12)

Catalog No. ABIN1885583

The Rabbit Polyclonal anti-SOCS5 antibody has been validated for WB and IHC. It is suitable to detect SOCS5 in samples from Human.

Quick Overview for SOCS5 antibody (AA 1-12) (ABIN1885583)

Target: SOCS5 (Suppressor of Cytokine Signaling 5 (SOCS5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOCS5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SOCS5 Antibody

Binding Specificity: AA 1-12

Purification: Purified by antigen-affinity chromatography.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 1 and 12 of SOCS5

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 1 x PBS, 40 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for SOCS5

Target: SOCS5 (Suppressor of Cytokine Signaling 5 (SOCS5))

Alternative Name: SOCS5

Background: The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain.The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family.SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling.The specific function of this protein has not yet been determined.Two alternatively spliced transcript variants encoding an identical protein have been reported.[provided by RefSeq]

Molecular Weight: 61 kDa

Gene ID: 9655

NCBI Accession: NP_054730, NM_014011

Pathways: JAK-STAT Signaling, EGFR Signaling Pathway, Positive Regulation of Immune Effector Process