SOCS5 antibody

Catalog No. ABIN7231440

The Rabbit Polyclonal anti-SOCS5 antibody (ABIN7231440) specifically detects SOCS5 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for SOCS5 antibody (ABIN7231440)

Target: SOCS5 (Suppressor of Cytokine Signaling 5 (SOCS5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOCS5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SOCS5 Antibody

Purpose: Rabbit Anti-SOCS5 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of SOCS5 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human SOCS5 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SOCS5

Target: SOCS5 (Suppressor of Cytokine Signaling 5 (SOCS5))

Alternative Name: SOCS5

Background: Suppressor of cytokine signaling 5, SOCS-5, Cytokine-inducible SH2 protein 6, CIS-6, Cytokine-inducible SH2-containing protein 5The protein encoded by SOCS5 (Suppressor Of Cytokine Signaling 5) contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported.

Molecular Weight: 58kD

Gene ID: 9655

UniProt: O75159

Pathways: JAK-STAT Signaling, EGFR Signaling Pathway, Positive Regulation of Immune Effector Process