LITAF antibody (AA 1-132)

Catalog No. ABIN1885606

This Rabbit Polyclonal antibody specifically detects LITAF in WB. It exhibits reactivity toward Human.

Quick Overview for LITAF antibody (AA 1-132) (ABIN1885606)

Target: LITAF (Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LITAF antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LITAF Antibody

Binding Specificity: AA 1-132

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 132 of Human LITAF

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for LITAF

Target: LITAF (Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))

Alternative Name: LITAF

Background: Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators.This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene.The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway.Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD).Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq]

Molecular Weight: 17 kDa

Gene ID: 9516

NCBI Accession: NM_004862, NP_004853

Pathways: Cellular Response to Molecule of Bacterial Origin