DAZ2 antibody (AA 1-207)

Catalog No. ABIN1885768

This Rabbit Polyclonal antibody specifically detects DAZ2 in WB and IF. It exhibits reactivity toward Human.

Quick Overview for DAZ2 antibody (AA 1-207) (ABIN1885768)

Target: DAZ2 (Deleted in Azoospermia 2 (DAZ2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAZ2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-DAZ2 Antibody

Binding Specificity: AA 1-207

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 207 of DAZ2

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for DAZ2

Target: DAZ2 (Deleted in Azoospermia 2 (DAZ2))

Alternative Name: DAZ2

Background: This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF).Its expression is restricted to premeiotic germ cells, particularly in spermatogonia.It encodes an RNA-binding protein that is important for spermatogenesis.Four copies of this gene are found on chromosome Y within palindromic duplications, one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome.Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat, the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat.Each copy of the gene also contains a 10.8 kb region that may be amplified, this region includes five exons that encode an RNA recognition motif (RRM) domain.This gene contains one copy of the 10.8 kb repeat.Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq]

Molecular Weight: 63 kDa

Gene ID: 57055

NCBI Accession: NM_020363, NP_065096