UNC13D antibody (AA 1029-1090)

Catalog No. ABIN1885943

The Rabbit Polyclonal anti-UNC13D antibody is suitable to detect UNC13D in samples from Human. It has been validated for WB, IHC and IF.

Quick Overview for UNC13D antibody (AA 1029-1090) (ABIN1885943)

Target: UNC13D (Unc-13 Homolog D (UNC13D))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UNC13D antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-UNC13D Antibody

Binding Specificity: AA 1029-1090

Purification: Purified by antigen-affinity chromatography.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 1029 and 1090 of Human UNC13D

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for UNC13D

Target: UNC13D (Unc-13 Homolog D (UNC13D))

Alternative Name: UNC13D

Background: This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins.The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion.Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.[provided by RefSeq]

Molecular Weight: 123 kDa

Gene ID: 201294

NCBI Accession: NP_954712, NM_199242

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process