AKAP12 antibody (AA 1719-1782)

Catalog No. ABIN1886110

This Rabbit Polyclonal antibody specifically detects AKAP12 in IHC, WB and IF. It exhibits reactivity toward Human.

Quick Overview for AKAP12 antibody (AA 1719-1782) (ABIN1886110)

Target: AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKAP12 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-AKAP12 Antibody

Binding Specificity: AA 1719-1782

Purification: Purified by antigen-affinity chromatography.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 1719 and 1782 of AKAP12

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for AKAP12

Target: AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))

Alternative Name: AKAP12

Background: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell.This gene encodes a member of the AKAP family.The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells.It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction.This protein and RII PKA colocalize at the cell periphery.This protein is a cell growth-related protein.Antibodies to this protein can be produced by patients with myasthenia gravis.Alternative splicing of this gene results in two transcript variants encoding different isoforms.[provided by RefSeq]

Molecular Weight: 192 kDa

Gene ID: 9590

NCBI Accession: NM_005100, NP_005091

Pathways: cAMP Metabolic Process