Factor VII antibody (AA 209-444)

Catalog No. ABIN1886186

The Rabbit Polyclonal anti-Factor VII antibody has been validated for WB and IHC. It is suitable to detect Factor VII in samples from Human and Mouse.

Quick Overview for Factor VII antibody (AA 209-444) (ABIN1886186)

Target: Factor VII (F7) (Coagulation Factor VII (F7))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Factor VII antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Factor VII Antibody

Binding Specificity: AA 209-444

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 209 and 444 of Factor VII

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for Factor VII

Target: Factor VII (F7) (Coagulation Factor VII (F7))

Alternative Name: Factor VII

Background: This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis.This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis.Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond.In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa.Alternative splicing of this gene results in 2 transcripts.Defects in this gene can cause coagulopathy.[provided by RefSeq]

Molecular Weight: 52 kDa

Gene ID: 2155

NCBI Accession: NP_000122, NM_000131

Pathways: Response to Growth Hormone Stimulus, Platelet-derived growth Factor Receptor Signaling