alpha Tubulin antibody (AA 227-450)

Catalog No. ABIN1886224

This Rabbit Polyclonal antibody specifically detects alpha Tubulin in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for alpha Tubulin antibody (AA 227-450) (ABIN1886224)

Target: alpha Tubulin (TUBA1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This alpha Tubulin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-alpha Tubulin Antibody

Binding Specificity: AA 227-450

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 227 and 450 of alpha Tubulin

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for alpha Tubulin

Target: alpha Tubulin (TUBA1)

Alternative Name: alpha Tubulin

Background: Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins.The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families.Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes.The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly.There are multiple alpha and beta tubulin genes, which are highly conserved among species.This gene encodes alpha tubulin and is highly similar to mouse and rat Tuba1 gene.Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells.This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q.[provided by RefSeq]

Molecular Weight: 50 kDa

Gene ID: 7846

Pathways: Microtubule Dynamics