DYRK3 antibody (AA 243-542)

Catalog No. ABIN1886254

This Rabbit Polyclonal antibody specifically detects DYRK3 in WB. It exhibits reactivity toward Human.

Quick Overview for DYRK3 antibody (AA 243-542) (ABIN1886254)

Target: DYRK3 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 (DYRK3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DYRK3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DYRK3 Antibody

Binding Specificity: AA 243-542

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 243 and 542 of Dyrk3

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for DYRK3

Target: DYRK3 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 (DYRK3))

Alternative Name: Dyrk3

Background: This gene product belongs to the DYRK family of dual-protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues.The members of this family share structural similarity, however, differ in their substrate , suggesting their involvement in different cellular functions.The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro.Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq]

Molecular Weight: 64 kDa

Gene ID: 8444

Pathways: Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha