CA9 antibody (AA 39-354)

Catalog No. ABIN1886428

This Rabbit Polyclonal antibody specifically detects CA9 in WB and IF. It exhibits reactivity toward Human.

Quick Overview for CA9 antibody (AA 39-354) (ABIN1886428)

Target: CA9 (Carbonic Anhydrase IX (CA9))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CA9 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-CA9 Antibody

Binding Specificity: AA 39-354

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 39 and 354 of Carbonic anhydrase 9

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for CA9

Target: CA9 (Carbonic Anhydrase IX (CA9))

Alternative Name: Carbonic anhydrase 9

Background: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide.They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid.They show extensive diversity in tissue distribution and in their subcellular localization.CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known.It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues.It may be involved in cell proliferation and transformation.This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12.[provided by RefSeq]
Synonyms: CAIX, MN

Molecular Weight: 50 kDa

Gene ID: 768

NCBI Accession: NP_001207, NM_001216