Cyclin T2 antibody (AA 497-707)
Quick Overview for Cyclin T2 antibody (AA 497-707) (ABIN1886514)
Target
See all Cyclin T2 (CCNT2) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 497-707
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Purification
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 497 and 707 of cyclin T2
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Application Notes
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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Preservative
- Thimerosal (Merthiolate)
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Precaution of Use
- Biohazard Informations: This product contains thimerosal which is hazardous.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Cyclin T2 (CCNT2)
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Alternative Name
- cyclin T2
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Background
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The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle.Cyclins function as regulators of CDK kinases.Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event.This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb.The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein.Two alternatively spliced transcript variants, which encode distinct isoforms, have been described.[provided by RefSeq]
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Molecular Weight
- 81 kDa
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Gene ID
- 905
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NCBI Accession
- NP_490595, NM_058241
Target
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