Fatty Acid Synthase antibody (AA 7-257)
Quick Overview for Fatty Acid Synthase antibody (AA 7-257) (ABIN1886623)
Target
See all Fatty Acid Synthase (FASN) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 7-257
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Purification
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 7 and 257 of Fatty Acid Synthase
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Application Notes
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.500
Immunofluorescence: 1.100-1.200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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Preservative
- Thimerosal (Merthiolate)
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Precaution of Use
- Biohazard Informations: This product contains thimerosal which is hazardous.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Fatty Acid Synthase (FASN)
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Alternative Name
- Fatty Acid Synthase
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Background
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The enzyme encoded by this gene is a multifunctional protein.Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids.In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.[provided by RefSeq]
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Molecular Weight
- 273 kDa
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Gene ID
- 2194
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NCBI Accession
- NP_004095, NM_004104
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Pathways
- AMPK Signaling
Target
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