BCL2L10 antibody (AA 70-133)

Catalog No. ABIN1886624

The Rabbit Polyclonal anti-BCL2L10 antibody is suitable to detect BCL2L10 in samples from Human. It has been validated for WB, IHC and IF.

Quick Overview for BCL2L10 antibody (AA 70-133) (ABIN1886624)

Target: BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCL2L10 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-BCL2L10 Antibody

Binding Specificity: AA 70-133

Purification: Purified by antigen-affinity chromatography.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 70 and 133 of BCL2L10

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for BCL2L10

Target: BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))

Alternative Name: BCL2L10

Background: The protein encoded by this gene belongs to the BCL-2 protein family.BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities.The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains.This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX.Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation.The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway.[provided by RefSeq]

Molecular Weight: 23 kDa

Gene ID: 10017

NCBI Accession: NM_020396, NP_065129

Pathways: Positive Regulation of Endopeptidase Activity