Cathepsin D antibody (AA 72-262)
Quick Overview for Cathepsin D antibody (AA 72-262) (ABIN1886634)
Target
See all Cathepsin D (CTSD) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 72-262
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Purification
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 72 and 262 of Human CTSD
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Application Notes
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500 -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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Preservative
- Thimerosal (Merthiolate)
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Precaution of Use
- Biohazard Informations: This product contains thimerosal which is hazardous.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Cathepsin D (CTSD)
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Alternative Name
- cathepsin D
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Background
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This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor.This proteinase, which is a member of the peptidase C1 family, has asimilar to but narrower than that of pepsin A.Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript.Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease.[provided by RefSeq]
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Molecular Weight
- 45 kDa
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Gene ID
- 1509
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NCBI Accession
- NP_001900, NM_001909
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Pathways
- Peptide Hormone Metabolism
Target
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