NSRP1 antibody (C-Term)

Catalog No. ABIN1887131

The Rabbit Polyclonal anti-NSRP1 antibody has been validated for WB and ELISA. It is suitable to detect NSRP1 in samples from Human, Mouse and Rat.

Quick Overview for NSRP1 antibody (C-Term) (ABIN1887131)

Target: NSRP1 (Nuclear Speckle Splicing Regulatory Protein 1 (NSRP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NSRP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-NSRP1 Antibody

Binding Specificity: C-Term

Specificity: At least three isoforms are known to exist, this antibody will detect all three.

Purification: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide near the carboxy terminus of human CCDC55.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for NSRP1

Target: NSRP1 (Nuclear Speckle Splicing Regulatory Protein 1 (NSRP1))

Alternative Name: CCDC55

Background: CCDC55, also known as Nuclear speckle-related protein 70 (NSrp70), was initially identified by the NIH Mammalian Gene Collection.Nuclear speckles are known to be the storage sites of mRNA splicing regulators.CCDC55 has been suggested to modulate alternative pre-mRNA splicing in vivo.It co-localizes and physically interacts with the SR proteins SC35 and ASF/SF2, essential splicing factors which are required for constitutive splicing and can regulate alternative mRNA splicing.Loss of CCDC55 in mice leads to early embryonic lethality highlights the importance of the functional role of CCDC55.
Synonyms: Coiled-coil domain-containing protein 55, HSPC095, NSrp70

NCBI Accession: NP_115517