FBXW7 antibody (AA 50-100)

Catalog No. ABIN1895375

The Rabbit Polyclonal anti-FBXW7 antibody has been validated for IHC, IHC (p), IP and IF. It is suitable to detect FBXW7 in samples from Human and Monkey.

Quick Overview for FBXW7 antibody (AA 50-100) (ABIN1895375)

Target: FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXW7 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunofluorescence (IF)

Product Details anti-FBXW7 Antibody

Binding Specificity: AA 50-100

Specificity: Region between residue 50 and 100 of human F-box and WD-40 domain protein 7 using the numbering given in entry NP_361014.1 (GeneID 55294).

Purification: Immunoaffinity purified

Isotype: IgG

Application Details

Application Notes: Approved: IF (1:250 - 1:2000), IHC, IHC-P (1:500 - 1:2000), IP (2 - 5 μg/mg lysate)

Usage: Immunohistochemistry: Antigen retrieval with citrate buffer  pH 6.0 is recommended for FFPE tissue sections. Human controls: Breast Carcinoma, Colon Carcinoma, Ovarian Carcinoma, Prostate Carcinoma.

Not recommended for: WB

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-citrate/phosphate buffer,  pH 7-8, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C for up to 1 year.

Expiry Date: 12 months

Target Details for FBXW7

Target: FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))

Alternative Name: FBXW7 / FBW7

Background: Name/Gene ID: FBXW7
Family: F-Box

Synonyms: FBXW7, AGO, Archipelago homolog, Archipelago, CDC4, F-box protein FBW7, FBXW6, F-box protein FBX30, F-box protein SEL-10, HCdc4, Homolog of C elegans sel-10, FBW6, FBX30, FBW7, HAgo, SEL-10, SEL10

Gene ID: 55294

Pathways: Notch Signaling, EGFR Signaling Pathway